Diazepam — Drug Interactions, Alcohol & Pregnancy Guide

Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team

Key Takeaways
  • Diazepam is a Benzodiazepine used for Anxiety.
  • Alcohol: Never mix diazepam and alcohol — both are CNS depressants and together can cause respiratory failure and death.
  • Pregnancy: Avoid diazepam in pregnancy — it is associated with neonatal withdrawal syndrome and respiratory depression in the newborn.
  • This page covers 3 specific drug combinations with Diazepam.

About Diazepam

Diazepam (Valium) is a benzodiazepine prescribed for anxiety, muscle spasm, and alcohol withdrawal. It is a controlled drug (Class C, Schedule 4) in the UK. It carries significant dependence risk and should only be used short-term.

Also sold as: Valium, Stesolid, Diazemuls

Drug class Benzodiazepine
Used for Anxiety, Muscle spasm, Alcohol withdrawal, Seizures, Procedure sedation
Max adult dose 2-10mg two to four times daily for anxiety; dose varies by indication
OTC in UK Prescription only

Diazepam at a glance

Diazepam is classed as benzodiazepine and is used for anxiety, muscle spasm, alcohol withdrawal, seizures, procedure sedation. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.

Typical adult dosing guidance: 2-10mg two to four times daily for anxiety; dose varies by indication. Your own label or prescription always takes priority over general figures.

Interactions most often flagged

  • Alcohol
  • Codeine
  • Tramadol
  • Zopiclone
  • Sertraline
  • Pregnancy

Before you combine Diazepam with anything new

  • Read the patient information leaflet for both products.
  • Keep one up-to-date list of every medicine and supplement you take.
  • Ask a pharmacist — it is free and takes a couple of minutes.
  • Seek urgent medical help if you feel seriously unwell after combining medicines.

Diazepam and Alcohol

🔴 AVOID

Never mix diazepam and alcohol — both are CNS depressants and together can cause respiratory failure and death.

Full guide →

Diazepam in Pregnancy

🔴 AVOID

Avoid diazepam in pregnancy — it is associated with neonatal withdrawal syndrome and respiratory depression in the newborn.

Full guide →

Diazepam — Drug Combinations

More in this category: anxiolytics

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Frequently Asked Questions

What is Diazepam used for?

Diazepam is a Benzodiazepine used for Anxiety, Muscle spasm, Alcohol withdrawal, Seizures, Procedure sedation.

What is the maximum adult dose of Diazepam?

The maximum adult dose is 2-10mg two to four times daily for anxiety; dose varies by indication. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.

Can I drink alcohol with Diazepam?

Never mix diazepam and alcohol — both are CNS depressants and together can cause respiratory failure and death.

Is Diazepam safe to take during pregnancy?

Avoid diazepam in pregnancy — it is associated with neonatal withdrawal syndrome and respiratory depression in the newborn.

Is Diazepam available over the counter in the UK?

Diazepam is prescription-only in the UK.

What should I check before taking Diazepam with other medicines?

The interactions most often flagged for Diazepam are: alcohol, codeine, tramadol, zopiclone, sertraline, pregnancy. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.

What are the brand names for Diazepam?

Diazepam is sold under brand names including Valium, Stesolid, Diazemuls. The active ingredient is the same, so check labels carefully to avoid doubling up on it.

Do I need a prescription for Diazepam?

Diazepam is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.

👨‍⚕️

Not sure if Diazepam is safe with your other medications?

HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.

Check your levels at HealthLabs →

Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.