Metformin — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Metformin is a Biguanide antidiabetic used for Type 2 diabetes.
- Alcohol: Avoid alcohol with metformin — it significantly increases the risk of lactic acidosis, a rare but serious complication.
- Pregnancy: Metformin is sometimes continued or started in pregnancy for gestational diabetes — but requires close medical supervision.
- This page covers 3 specific drug combinations with Metformin.
About Metformin
Metformin is the first-line medication for type 2 diabetes in the UK. It lowers blood glucose by reducing hepatic glucose production. It is also used for PCOS and gestational diabetes. Rare risk of lactic acidosis with heavy alcohol use or kidney impairment.
Also sold as: Glucophage, Bolamyn
Metformin at a glance
Metformin is classed as biguanide antidiabetic and is used for type 2 diabetes, gestational diabetes, pcos. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.
Typical adult dosing guidance: 500mg-1g two or three times daily with meals, maximum 3g daily. Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Ibuprofen
- Alcohol
- Pregnancy
Before you combine Metformin with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Metformin and Alcohol
Avoid alcohol with metformin — it significantly increases the risk of lactic acidosis, a rare but serious complication.
Full guide →Metformin in Pregnancy
Metformin is sometimes continued or started in pregnancy for gestational diabetes — but requires close medical supervision.
Full guide →Metformin — Drug Combinations
⭐ Recommended on Amazon
Weekly Pill Organiser
Keep track of multiple medications with a clear 7-day pill box — reduces missed and double doses.
View on Amazon →Medication Record Book
Log your medications, doses and times to stay safe and flag any concerns to your pharmacist.
View on Amazon →Lockable Medicine Cabinet
Store all your medications safely in one place, out of reach of children.
View on Amazon →Affiliate links below. This page contains affiliate links through Amazon and CJ Affiliate. As an Amazon Associate we earn from qualifying purchases. We may earn a commission if you buy through them, at no extra cost to you.
Frequently Asked Questions
What is Metformin used for?
Metformin is a Biguanide antidiabetic used for Type 2 diabetes, Gestational diabetes, PCOS.
What is the maximum adult dose of Metformin?
The maximum adult dose is 500mg-1g two or three times daily with meals, maximum 3g daily. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Can I drink alcohol with Metformin?
Avoid alcohol with metformin — it significantly increases the risk of lactic acidosis, a rare but serious complication.
Is Metformin safe to take during pregnancy?
Metformin is sometimes continued or started in pregnancy for gestational diabetes — but requires close medical supervision.
Is Metformin available over the counter in the UK?
Metformin is prescription-only in the UK.
What should I check before taking Metformin with other medicines?
The interactions most often flagged for Metformin are: ibuprofen, alcohol, pregnancy. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Metformin?
Metformin is sold under brand names including Glucophage, Bolamyn. The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Metformin?
Metformin is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.
Not sure if Metformin is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.