Prednisolone — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Prednisolone is a Corticosteroid used for Asthma and COPD exacerbations.
- Alcohol: Alcohol and prednisolone both irritate the stomach lining — together they significantly raise the risk of stomach ulcers and GI bleeding, especially with longer courses.
- This page covers 1 specific drug combination with Prednisolone.
About Prednisolone
Prednisolone is a corticosteroid used to reduce inflammation and suppress the immune system. It is used for a wide range of conditions. Long-term use has significant side effects including bone thinning, immune suppression, and blood sugar elevation.
Also sold as: Deltacortril, Deltastab, Predsol
Prednisolone at a glance
Prednisolone is classed as corticosteroid and is used for asthma and copd exacerbations, inflammatory conditions, autoimmune diseases, allergic reactions, transplant immunosuppression. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.
Typical adult dosing guidance: 5-60mg daily depending on condition; short courses for acute conditions. Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Ibuprofen
- Aspirin
- Alcohol
- Pregnancy
Before you combine Prednisolone with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Prednisolone and Alcohol
Alcohol and prednisolone both irritate the stomach lining — together they significantly raise the risk of stomach ulcers and GI bleeding, especially with longer courses.
Full guide →Prednisolone — Drug Combinations
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Frequently Asked Questions
What is Prednisolone used for?
Prednisolone is a Corticosteroid used for Asthma and COPD exacerbations, Inflammatory conditions, Autoimmune diseases, Allergic reactions, Transplant immunosuppression.
What is the maximum adult dose of Prednisolone?
The maximum adult dose is 5-60mg daily depending on condition; short courses for acute conditions. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Can I drink alcohol with Prednisolone?
Alcohol and prednisolone both irritate the stomach lining — together they significantly raise the risk of stomach ulcers and GI bleeding, especially with longer courses.
Is Prednisolone available over the counter in the UK?
Prednisolone is prescription-only in the UK.
What should I check before taking Prednisolone with other medicines?
The interactions most often flagged for Prednisolone are: ibuprofen, aspirin, alcohol, pregnancy. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Prednisolone?
Prednisolone is sold under brand names including Deltacortril, Deltastab, Predsol. The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Prednisolone?
Prednisolone is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.
Not sure if Prednisolone is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.