Montelukast — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Montelukast is a Leukotriene receptor antagonist used for Asthma.
- Alcohol: No significant interaction between montelukast and alcohol — moderate drinking is generally fine, though alcohol is itself a trigger for asthma in many people.
- This page covers 1 specific drug combination with Montelukast.
About Montelukast
Montelukast is a leukotriene receptor antagonist used as add-on therapy in asthma and for allergic rhinitis. The FDA has issued a black box warning for neuropsychiatric effects (mood changes, depression, suicidal ideation) — particularly in children.
Also sold as: Singulair
Montelukast at a glance
Montelukast is classed as leukotriene receptor antagonist and is used for asthma, allergic rhinitis, exercise-induced bronchospasm. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.
Typical adult dosing guidance: 10mg once daily in the evening. Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Phenobarbital (reduces levels)
Before you combine Montelukast with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Montelukast and Alcohol
No significant interaction between montelukast and alcohol — moderate drinking is generally fine, though alcohol is itself a trigger for asthma in many people.
Full guide →Montelukast — Drug Combinations
More in this category: respiratory
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Frequently Asked Questions
What is Montelukast used for?
Montelukast is a Leukotriene receptor antagonist used for Asthma, Allergic rhinitis, Exercise-induced bronchospasm.
What is the maximum adult dose of Montelukast?
The maximum adult dose is 10mg once daily in the evening. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Can I drink alcohol with Montelukast?
No significant interaction between montelukast and alcohol — moderate drinking is generally fine, though alcohol is itself a trigger for asthma in many people.
Is Montelukast available over the counter in the UK?
Montelukast is prescription-only in the UK.
What should I check before taking Montelukast with other medicines?
The interactions most often flagged for Montelukast are: phenobarbital (reduces levels). Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Montelukast?
Montelukast is sold under brand names including Singulair. The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Montelukast?
Montelukast is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.
Not sure if Montelukast is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.