Amlodipine — Drug Interactions, Alcohol & Pregnancy Guide

Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team

Key Takeaways
  • Amlodipine is a Calcium channel blocker used for High blood pressure.
  • Alcohol: Alcohol can enhance amlodipine's blood-pressure-lowering effect, causing dizziness or faintness — moderate drinking is usually fine but heavy drinking should be avoided.
  • This page covers 2 specific drug combinations with Amlodipine.

About Amlodipine

Amlodipine is a calcium channel blocker for high blood pressure and angina. It is well tolerated but can cause ankle swelling (peripheral oedema) and facial flushing. It is taken once daily.

Also sold as: Norvasc, Istin

Drug class Calcium channel blocker
Used for High blood pressure, Angina
Max adult dose 5-10mg once daily
OTC in UK Prescription only

Amlodipine at a glance

Amlodipine is classed as calcium channel blocker and is used for high blood pressure, angina. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.

Typical adult dosing guidance: 5-10mg once daily. Your own label or prescription always takes priority over general figures.

Interactions most often flagged

  • Alcohol
  • Grapefruit juice
  • Simvastatin

Before you combine Amlodipine with anything new

  • Read the patient information leaflet for both products.
  • Keep one up-to-date list of every medicine and supplement you take.
  • Ask a pharmacist — it is free and takes a couple of minutes.
  • Seek urgent medical help if you feel seriously unwell after combining medicines.

Amlodipine and Alcohol

🟡 USE WITH CAUTION

Alcohol can enhance amlodipine's blood-pressure-lowering effect, causing dizziness or faintness — moderate drinking is usually fine but heavy drinking should be avoided.

Full guide →

Amlodipine — Drug Combinations

More in this category: cardiovascular

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Frequently Asked Questions

What is Amlodipine used for?

Amlodipine is a Calcium channel blocker used for High blood pressure, Angina.

What is the maximum adult dose of Amlodipine?

The maximum adult dose is 5-10mg once daily. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.

Can I drink alcohol with Amlodipine?

Alcohol can enhance amlodipine's blood-pressure-lowering effect, causing dizziness or faintness — moderate drinking is usually fine but heavy drinking should be avoided.

Is Amlodipine available over the counter in the UK?

Amlodipine is prescription-only in the UK.

What should I check before taking Amlodipine with other medicines?

The interactions most often flagged for Amlodipine are: alcohol, grapefruit juice, simvastatin. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.

What are the brand names for Amlodipine?

Amlodipine is sold under brand names including Norvasc, Istin. The active ingredient is the same, so check labels carefully to avoid doubling up on it.

Do I need a prescription for Amlodipine?

Amlodipine is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.

👨‍⚕️

Not sure if Amlodipine is safe with your other medications?

HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.

Check your levels at HealthLabs →

Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.