Lisinopril — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Lisinopril is a ACE Inhibitor used for High blood pressure.
- Alcohol: Alcohol can increase lisinopril's blood-pressure-lowering effect — occasional moderate drinking is usually tolerated, but heavy drinking raises kidney and cardiovascular risks.
- Pregnancy: Lisinopril must be stopped in pregnancy — all ACE inhibitors damage fetal kidneys and should be switched to a safe blood pressure alternative as soon as possible.
About Lisinopril
Lisinopril is an ACE inhibitor used for high blood pressure and heart failure. It is contraindicated in pregnancy (can cause fetal kidney damage). It can cause a dry persistent cough in approximately 10-20% of patients.
Also sold as: Zestril, Carace, Lisoretic (with hydrochlorothiazide)
Lisinopril at a glance
Lisinopril is classed as ace inhibitor and is used for high blood pressure, heart failure, diabetic nephropathy prevention. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.
Typical adult dosing guidance: 10-40mg once daily for hypertension. Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Ibuprofen
- Aspirin
- Alcohol
- Pregnancy
- Potassium supplements
Before you combine Lisinopril with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Lisinopril and Alcohol
Alcohol can increase lisinopril's blood-pressure-lowering effect — occasional moderate drinking is usually tolerated, but heavy drinking raises kidney and cardiovascular risks.
Full guide →Lisinopril in Pregnancy
Lisinopril must be stopped in pregnancy — all ACE inhibitors damage fetal kidneys and should be switched to a safe blood pressure alternative as soon as possible.
Full guide →More in this category: cardiovascular
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Frequently Asked Questions
What is Lisinopril used for?
Lisinopril is a ACE Inhibitor used for High blood pressure, Heart failure, Diabetic nephropathy prevention.
What is the maximum adult dose of Lisinopril?
The maximum adult dose is 10-40mg once daily for hypertension. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Can I drink alcohol with Lisinopril?
Alcohol can increase lisinopril's blood-pressure-lowering effect — occasional moderate drinking is usually tolerated, but heavy drinking raises kidney and cardiovascular risks.
Is Lisinopril safe to take during pregnancy?
Lisinopril must be stopped in pregnancy — all ACE inhibitors damage fetal kidneys and should be switched to a safe blood pressure alternative as soon as possible.
Is Lisinopril available over the counter in the UK?
Lisinopril is prescription-only in the UK.
What should I check before taking Lisinopril with other medicines?
The interactions most often flagged for Lisinopril are: ibuprofen, aspirin, alcohol, pregnancy, potassium supplements. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Lisinopril?
Lisinopril is sold under brand names including Zestril, Carace, Lisoretic (with hydrochlorothiazide). The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Lisinopril?
Lisinopril is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.
Not sure if Lisinopril is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.