Metoprolol — Drug Interactions, Alcohol & Pregnancy Guide

Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team

Key Takeaways
  • Metoprolol is a Beta-1 selective beta-blocker used for Hypertension.
  • Alcohol: Alcohol can enhance metoprolol's blood-pressure-lowering and heart-rate-slowing effects — occasional moderate drinking is usually tolerated, but avoid heavy drinking.
  • Pregnancy: Metoprolol is sometimes used in pregnancy for hypertension and arrhythmia under specialist supervision — labetalol is generally preferred as the first-choice beta-blocker.

About Metoprolol

Metoprolol is a cardioselective beta-blocker for heart conditions and blood pressure. Available as immediate-release (twice daily) and extended-release (once daily: metoprolol succinate). Do not stop suddenly.

Also sold as: Lopressor, Betaloc

Drug class Beta-1 selective beta-blocker
Used for Hypertension, Angina, Heart failure, Atrial fibrillation, Migraine prevention
Max adult dose 50-200mg twice daily (immediate release)
OTC in UK Prescription only

Metoprolol at a glance

Metoprolol is classed as beta-1 selective beta-blocker and is used for hypertension, angina, heart failure, atrial fibrillation, migraine prevention. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.

Typical adult dosing guidance: 50-200mg twice daily (immediate release). Your own label or prescription always takes priority over general figures.

Interactions most often flagged

  • Alcohol
  • Verapamil

Before you combine Metoprolol with anything new

  • Read the patient information leaflet for both products.
  • Keep one up-to-date list of every medicine and supplement you take.
  • Ask a pharmacist — it is free and takes a couple of minutes.
  • Seek urgent medical help if you feel seriously unwell after combining medicines.

Metoprolol and Alcohol

🟡 USE WITH CAUTION

Alcohol can enhance metoprolol's blood-pressure-lowering and heart-rate-slowing effects — occasional moderate drinking is usually tolerated, but avoid heavy drinking.

Full guide →

Metoprolol in Pregnancy

🟡 USE WITH CAUTION

Metoprolol is sometimes used in pregnancy for hypertension and arrhythmia under specialist supervision — labetalol is generally preferred as the first-choice beta-blocker.

Full guide →

More in this category: cardiovascular

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Frequently Asked Questions

What is Metoprolol used for?

Metoprolol is a Beta-1 selective beta-blocker used for Hypertension, Angina, Heart failure, Atrial fibrillation, Migraine prevention.

What is the maximum adult dose of Metoprolol?

The maximum adult dose is 50-200mg twice daily (immediate release). This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.

Can I drink alcohol with Metoprolol?

Alcohol can enhance metoprolol's blood-pressure-lowering and heart-rate-slowing effects — occasional moderate drinking is usually tolerated, but avoid heavy drinking.

Is Metoprolol safe to take during pregnancy?

Metoprolol is sometimes used in pregnancy for hypertension and arrhythmia under specialist supervision — labetalol is generally preferred as the first-choice beta-blocker.

Is Metoprolol available over the counter in the UK?

Metoprolol is prescription-only in the UK.

What should I check before taking Metoprolol with other medicines?

The interactions most often flagged for Metoprolol are: alcohol, verapamil. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.

What are the brand names for Metoprolol?

Metoprolol is sold under brand names including Lopressor, Betaloc. The active ingredient is the same, so check labels carefully to avoid doubling up on it.

Do I need a prescription for Metoprolol?

Metoprolol is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.

👨‍⚕️

Not sure if Metoprolol is safe with your other medications?

HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.

Check your levels at HealthLabs →

Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.