Clopidogrel — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Clopidogrel is a Antiplatelet agent (P2Y12 inhibitor) used for Prevention of heart attack.
- This page covers 1 specific drug combination with Clopidogrel.
About Clopidogrel
Clopidogrel is an antiplatelet drug — it prevents platelets from clumping together. It requires activation by CYP2C19 (reduced by omeprazole). Do not stop without medical advice after a stent.
Also sold as: Plavix
Clopidogrel at a glance
Clopidogrel is classed as antiplatelet agent (p2y12 inhibitor) and is used for prevention of heart attack, prevention of stroke, after coronary stent placement, peripheral arterial disease. It is a prescription medicine, so doses and combinations should always be agreed with your prescriber or pharmacist.
Typical adult dosing guidance: 75mg once daily (300-600mg loading dose). Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Omeprazole (avoid)
- Aspirin
- Nsaids
- Alcohol
- Pregnancy
Before you combine Clopidogrel with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Clopidogrel — Drug Combinations
More in this category: cardiovascular
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Frequently Asked Questions
What is Clopidogrel used for?
Clopidogrel is a Antiplatelet agent (P2Y12 inhibitor) used for Prevention of heart attack, Prevention of stroke, After coronary stent placement, Peripheral arterial disease.
What is the maximum adult dose of Clopidogrel?
The maximum adult dose is 75mg once daily (300-600mg loading dose). This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Is Clopidogrel available over the counter in the UK?
Clopidogrel is prescription-only in the UK.
What should I check before taking Clopidogrel with other medicines?
The interactions most often flagged for Clopidogrel are: omeprazole (avoid), aspirin, NSAIDs, alcohol, pregnancy. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Clopidogrel?
Clopidogrel is sold under brand names including Plavix. The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Clopidogrel?
Clopidogrel is a prescription medicine, so take it exactly as your prescriber directed and ask them before changing the dose.
Not sure if Clopidogrel is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.