Loratadine — Drug Interactions, Alcohol & Pregnancy Guide
Last reviewed: · Source: US FDA drug label database · 247CanITakeWith Editorial Team
- Loratadine is a Second-generation antihistamine used for Hay fever.
- Alcohol: Generally low risk — loratadine is one of the least sedating antihistamines, but combining with alcohol can still increase drowsiness for some people.
- Pregnancy: Loratadine is the first-choice antihistamine in pregnancy in UK guidance — large studies show no pattern of harm.
- This page covers 1 specific drug combination with Loratadine.
About Loratadine
Loratadine is one of the least sedating antihistamines available. It is a preferred choice for people who need to drive or operate machinery. It takes effect within 1-3 hours and lasts 24 hours.
Also sold as: Claritin, Clarityn
Loratadine at a glance
Loratadine is classed as second-generation antihistamine and is used for hay fever, allergic rhinitis, urticaria. It can be bought over the counter in the UK, but that does not mean it is safe with everything — check the label and ask a pharmacist if you take other medicines.
Typical adult dosing guidance: 10mg once daily. Your own label or prescription always takes priority over general figures.
Interactions most often flagged
- Alcohol
Before you combine Loratadine with anything new
- Read the patient information leaflet for both products.
- Keep one up-to-date list of every medicine and supplement you take.
- Ask a pharmacist — it is free and takes a couple of minutes.
- Seek urgent medical help if you feel seriously unwell after combining medicines.
Loratadine and Alcohol
Generally low risk — loratadine is one of the least sedating antihistamines, but combining with alcohol can still increase drowsiness for some people.
Full guide →Loratadine in Pregnancy
Loratadine is the first-choice antihistamine in pregnancy in UK guidance — large studies show no pattern of harm.
Full guide →Loratadine — Drug Combinations
More in this category: allergy
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Frequently Asked Questions
What is Loratadine used for?
Loratadine is a Second-generation antihistamine used for Hay fever, Allergic rhinitis, Urticaria.
What is the maximum adult dose of Loratadine?
The maximum adult dose is 10mg once daily. This is general guidance — always follow the dose on your prescription or product label, and check with a pharmacist if you're unsure.
Can I drink alcohol with Loratadine?
Generally low risk — loratadine is one of the least sedating antihistamines, but combining with alcohol can still increase drowsiness for some people.
Is Loratadine safe to take during pregnancy?
Loratadine is the first-choice antihistamine in pregnancy in UK guidance — large studies show no pattern of harm.
Is Loratadine available over the counter in the UK?
Yes, Loratadine is available over the counter in the UK.
What should I check before taking Loratadine with other medicines?
The interactions most often flagged for Loratadine are: alcohol. Tell your pharmacist or prescriber about everything you take, including over-the-counter products, supplements and herbal remedies, before combining it with anything new.
What are the brand names for Loratadine?
Loratadine is sold under brand names including Claritin, Clarityn. The active ingredient is the same, so check labels carefully to avoid doubling up on it.
Do I need a prescription for Loratadine?
Loratadine does not need a prescription in the UK, but a pharmacist can still advise whether it suits you alongside your other medicines.
Not sure if Loratadine is safe with your other medications?
HealthLabs.com lets you check liver enzyme or kidney function levels before combining medications long-term — no GP referral needed.
Check your levels at HealthLabs →Always speak to your pharmacist or GP for personalised medical advice. Affiliate link — we may earn a commission.